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Abstract | Cited by

An amphiphilic brush block copolymer P(St-g-PBDEMA)-b-P(MEO2MA-co-OEGMA) was prepared by ATRP, RAFT and click chemistry. The copolymer micelles show temperature and glucose responses. The controlled release of insulin could be achieved by adjusting temperature and glucose concentration.

Graphical abstract: Thermo- and glucose-responsive micelles self-assembled from phenylborate ester-containing brush block copolymer for controlled release of insulin at physiological pH

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