Issue 70, 2015
From the journal:

RSC Advances

An efficient condensation of substituted salicylaldehyde and malononitrile catalyzed by lipase under microwave irradiation†

Fengjuan Yang,‡ab   Zhi Wang,‡ab   Haoran Wang,ab   Chunyu Wang*c  and  Lei Wang*ab  

* Corresponding authors

a Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education, Jilin University, Changchun 130023, P R China
E-mail: w_lei@jlu.edu.cn

b College of Life Science, Jilin University, Changchun 130023, P R China

c State Key Laborarory of Supramolecular Structure and Materials, Jilin University, Changchun 130023, China
E-mail: chunyu@jlu.edu.cn

Abstract

The present work illustrates the condensation of substituted salicylaldehyde and malononitrile catalyzed by lipase under microwave irradiation. The reaction obtains two different products by a delicate control of the substrate molar ratio and reaction time. This protocol has the advantages of high yield, short reaction time and environmental friendliness.

Graphical abstract: An efficient condensation of substituted salicylaldehyde and malononitrile catalyzed by lipase under microwave irradiation

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Article information

DOI
https://doi.org/10.1039/C5RA10565J
Article type
Communication
Submitted
04 Jun 2015
Accepted
25 Jun 2015
First published
25 Jun 2015

RSC Adv., 2015,5, 57122-57126

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An efficient condensation of substituted salicylaldehyde and malononitrile catalyzed by lipase under microwave irradiation

F. Yang, Z. Wang, H. Wang, C. Wang and L. Wang, RSC Adv., 2015, 5, 57122 DOI: 10.1039/C5RA10565J

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