Issue 37, 2015

Microwave-assisted palladium-catalysed isonitrile insertion in 2-bromophenylureas for efficient synthesis of 4-substituted imino 4H-benzo[d][1,3]oxazin-2-amines

Abstract

A general route to the synthesis of 4-substituted imino 4H-benzo[d][1,3]oxazin-2-amines via palladium-catalysed isonitrile insertion in 2-bromophenylureas succeeded by a C–O cross-coupling of the intermediate imidoylpalladium species under microwave irradiation is reported.

Graphical abstract: Microwave-assisted palladium-catalysed isonitrile insertion in 2-bromophenylureas for efficient synthesis of 4-substituted imino 4H-benzo[d][1,3]oxazin-2-amines

Associated articles

Supplementary files

Article information

Article type
Communication
Submitted
17 Feb 2015
Accepted
18 Mar 2015
First published
18 Mar 2015

RSC Adv., 2015,5, 28875-28878

Author version available

Microwave-assisted palladium-catalysed isonitrile insertion in 2-bromophenylureas for efficient synthesis of 4-substituted imino 4H-benzo[d][1,3]oxazin-2-amines

G. Pandey and S. Batra, RSC Adv., 2015, 5, 28875 DOI: 10.1039/C5RA03062E

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