Electrochemically assisted micro localized grafting of aptamers in a microchannel engraved in fluorinated thermoplastic polymer Dyneon THV

Abstract

The surface modification of the bottom of a microchannel of a new family of microfluidic chip materials, fluorinated thermoplastic polymer (Dyneon THV), was performed for the first time through the local electrochemical carbonization of the polymer followed by the adsorption of azide-bearing diazonium moieties and the covalent linkage of alkyne-bearing aptamers through the click chemistry reaction.