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A concise synthesis of single components of C2 sulfated oligomannans including trimers, tetramers, and pentamers is reported. The synthesis features the application of the DMF-modulation method for the participatory thiomannoside donors in 1,2-trans α-glycosidic bond formation. The obtained oligomannans were fully characterized using 1H, 13C, COSY, and HSQC NMR spectroscopy.

Graphical abstract: A concise synthesis of single components of partially sulfated oligomannans

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