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Organo-modified mesoporous silica nanoparticles, loaded with ibuprofen into the pores and functionalized on the external surface with a stable Gd(III)–DOTA-monoamide chelate, were prepared and explored as potential theranostic probes.

Graphical abstract: Selective functionalization of mesoporous silica nanoparticles with ibuprofen and Gd(iii) chelates: a new probe for potential theranostic applications

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