Kishor
Naktode
a,
Jayeeta
Bhattacharjee
a,
Hari Pada
Nayek
b and
Tarun K.
Panda
*a
aDepartment of Chemistry, Indian Institute of Technology Hyderabad, Ordnance Factory Estate, Yeddumailaram 502205, Telangana, India. E-mail: tpanda@iith.ac.in; Fax: +91 (40) 2301 6032; Tel: +91 (40) 2301 6036
bDepartment of Applied Chemistry, Indian School of Mines, Dhanbad, 826004, Jharkhand, India
First published on 9th March 2015
The synthesis and isolation of two potassium, one lithium and two calcium complexes of imidazol-2-ylidene-N′-phenylureate ligands [ImRNCON(H)Ph] [(R = tBu (1a); Mes (1b) and Dipp (1c); Mes = mesityl, Dipp = 2,6-diisopropylphenyl] are described. Potassium complexes, [{κ2-(ImMesNCONPh)K}4] (2b) and [{κ3-(ImDippNCONPh)K}2{KN(SiMe3)2}2]n (2c), were prepared in good yields by the reactions of 1b and 1c, respectively, with potassium bis(trimethyl)silyl amide at ambient temperature in toluene. Lithium complex [{(2,6-tBu2-4-Me-C6H2O)Li(ImtBuNCON(H)Ph)}2{ImtBuNCON(H)Ph}] (3a) was isolated by a one-pot reaction between 1a and LiCH2SiMe3, followed by the addition of 2,6-tBu2-4-Me-C6H2OH in toluene. Calcium complex [{κ2-(ImtBuNCONPh)Ca{N(SiMe3)2}-{KN(SiMe3)2}]n (4a) was isolated by the one-pot reaction of 1a with [KN(SiMe3)2] and calcium diiodide in THF at ambient temperature. The solid-state structures of ligand 1a and complexes 2b, 2c, 3a and 4a were confirmed by single-crystal X-ray diffraction analysis. It was observed that potassium was coordinated to the oxygen atom of urea group and to the nitrogen atom of the imidazolin-2-imine group, in the solid-state structure of 2b. In complex 4a, the calcium ion was ligated to the monoanionic imidazol-2-ylidene-N′-phenylureate ligand in a bi-dentate (κ2) fashion through the oxygen and nitrogen atoms of the isocyanate building block leaving the imidazolin-2-imine fragment uncoordinated. In the solid state of the potassium complex 2c, tri-dentate (κ3) coordination from the imidazol-2-ylidene-N′-phenylureate ligand was observed through the oxygen and nitrogen atoms of the isocyanate building block and of the imidazolin-2-imine fragment. In contrast, in the dimeric lithium complex 3a, the neutral imidazol-2-ylidene-N′-phenylureate ligand was bound to the lithium centre in a mono-dentate fashion (κ1) through an oxygen atom of the isocyanate moiety. It is to be noted that in each complex thus observed, the elongated carbon–nitrogen bond distances indicate substantial electron delocalisation from the imidazole ring to the ureate group present in ligand 1.
The enhanced electron-donating capacity and high nucleophilicity observed in these carbenes are indicative of the capability of the imidazolium ring to effectively stabilise a positive charge. An analogous principle can be applied to organic imidazolin derivatives containing an exo-cyclic atom or an organic moiety X attached at the 2-position of the N-heterocycle such that, for species such as 2-methylene-, 2-imino-, 2-oxo- and 2-thioimidazolines (X = CH2, NH, O, S), a strong contribution from the ylidic mesomeric form 1B may be considered (Chart 1).5,6
It was established that, due to the resulting build-up of negative charge at the X atom due to the mesomeric form 1B, the atom X possesses enhanced basicity and nucleophilicity.7 In recent years, Tamm and co-workers exploited this concept by providing access to a large variety of novel imidazolin-2-imines (ImNH, X = NH) that can be used for the preparation of imidazolin-2-iminato complexes of transition metals and rare earth elements, and, more recently, of actinide metals, in order to achieve very short M–N bonds. This has led to the probability of a multiple bonding character between M–N bonds.8 The M–N bond possesses a multiple bonding character – its reactivity is described as being very similar to a MN imido bond.9 It has been observed that various metal complexes supported by imidazolin-2-iminato ligands display high activity in ethylene (co)polymerisation and in alkyne metathesis.10
Lavoie et al. recently reported the preparation of urea and the thio-urea derivatives imidazol-2-ylidene-N′-p-tolylureate and imidazol-2-ylidene-N′-p-tolylthioureate from imidazolin-2-imines and p-tolyl isocyanate and isothiocyanate, respectively.11 This family of neutral polydentate ligands incorporates the imidazolin-2-imine fragment in its fold. Lavoie et al. also introduced these urea- and thio-urea functionalised ligands into groups 4 and 10 in transition metal chemistry in order to explore their coordination behaviours. It was observed that these bi-dentate urea- and thio-urea functionalised ligands bound more electro positive titanium (Ti4+) ions through the nitrogen and oxygen atoms of the isocyanate building block, while leaving the imidazol-2-imine fragment uncoordinated. However, they found the lesser electropositive metal ions (Ni2+ and Pd2+) to be ligated through both the nitrogen atoms of the ligand. Nevertheless, their work was restricted to transition metal chemistry, and the structural aspects of alkali metal and alkaline earth metal complexes with these ligands have not been reported to date.
We earlier reported on phosphine-functionalised imidazolin-2-imines, imidazolin-2-ylidene-1,1-diphenylphosphine-amine and their chalcogenide derivatives (O, S, Se and Te).12 In our ongoing efforts to prepare functionalised imidazolin-2-imines, and with an interest to observe and record their coordination behaviour towards the main group organometallics, we prepared various alkali metal and alkaline earth metal complexes with imidazolin-2-imine urea derivatives.
It is in this context that herein we present the synthetic and structural details of two potassium complexes [{κ2-(ImMesNCONPh)K}4] (2b) and [{κ3-(ImDippNCONPh)K}2{KN(SiMe3)2}2]n (2c), one lithium complex (3a) and one calcium complex [{κ2-(ImtBuNCONPh)-Ca{N(SiMe3)2}{KN(SiMe3)2}]n (4a) of imidazol-2-ylidene-N′-phenylureate ligand [ImRNCON(H)Ph] [(R = tBu (1a); Mes (1b) and Dipp (1c); Mes = mesityl, Dipp = 2,6-diisopropylphenyl]. We also report the molecular structures of an imidazol-2-ylidene-N′-phenylthiourate ligand (1d) and a siloxane incorporated calcium complex [{κ3-(ImtBuNCONPh)}2Ca(OSiMe2OSiMe2O)2{κ3-(ImtBuNCONPh)CaK}2{KN(SiMe3)2}2{Ca(N(SiMe3)2)2}2]n (5a).
The 1H NMR spectra measured in C6D6 for the compounds 1a–c and CDCl3 (1d) are similar and show a characteristic singlet resonance [δ 6.18 (1a), 5.80 (1b), 6.10 (1c) and 6.22 (1d) ppm] for imidazolium backbone olefinic protons. These can be observed as a downfield shift from that of the respective imidazol-2-imines [δ 5.96 (tBu); 5.71 (Mes); 5.87 (Dipp) ppm]. The resonances for 18 protons from the six methyl groups in 1a appeared as singlets at δ 1.43 ppm, whereas two singlets at δ 2.26 and 2.05 ppm could be assigned to the o- and p-methyl protons, respectively, in the mesityl groups. The distinct septet signal at δ 3.21 ppm, and the two doublet resonances with a coupling constant 6.8 Hz each, appeared at δ 1.45 and 1.16 ppm, respectively, due to the –CH hydrogen and isopropyl methyl hydrogen atoms of the ligand 1c. The CO stretching frequencies [ν 1627 (1a), 1647 (1b), 1650 (1c) cm−1] were considerably lower than that of the starting isocyanate (2170 cm−1), indicating a marked reduction in C–O strength upon formation of the urea. As the observed stretching frequencies were also slightly lower than those commonly observed in organic amides13 – a manifestation of the electron delocalisation from the imidazole ring to the acyl group – a further decrease of the C–O bond order can be realised. The resonance for the tert-butyl methyl protons in compound 1d could be detected as a sharp singlet at δ 1.65 ppm. The strong absorption band at 1400–1600 cm−1 in the FT-IR spectrum of 1d indicated the presence of a CS group. However, the exact band was difficult to identify due to the mixing of the other vibration modes.14
Single crystals of 1a and 1d were obtained from the concentrated toluene solution of the respective compounds at ambient temperature. Compound 1a crystallised in the monoclinic space group P21/c with four molecules in the unit cell. In contrast, the thiourea derivative 1d crystallised in the trigonal space group R with 18 molecules in the unit cell. The details of the structural parameters are given in Table TS1 in the ESI.† The solid-state structure of complex 1a is shown in Fig. 1, whereas Fig. S1 in the ESI† represents the solid-state structure of 1d. The C1–N1 bond distance of 1.346(3) Å in 1a is elongated, compared to ImtBuNH [1.295(2) Å];15 presumably due to enhanced electron donation to the imino nitrogen atom from the imidazolium ring. A slight elongation of the carbonyl C12–O1 bond [1.236(3) Å] was observed due to the delocalisation of electrons from imino nitrogen to the oxygen atom of the isocyanate building block. The slightly shorter N1–C12 bond [1.339 (3) Å], compared to the N4–C12 bond [1.389(3) Å], is also supportive of the above delocalisation over the N1–C12–O1 unit on ligand 1a. Short hydrogen bonding between the electronegative oxygen atom and hydrogen atoms from adjacent methyl groups, O1⋯H5a (2.706 Å) and O1⋯H9c (2.541 Å), is also observed (Fig. 1).
The 1H NMR spectra of complexes 2b and 2c, measured in C6D6, revealed one set of signals in each case. The two olefinic protons of the imidazole backbone resonated at δ 5.80 (2b) and 5.95 ppm (2c), respectively. These in a similar range to those of the starting urea ligands (5.80 ppm for 1b and 6.10 ppm for 1c). The methyl protons of the mesityl groups in 2b were observed to resonate at δ 2.26 and 2.06 ppm as two sharp singlets. Furthermore, in complex 2c, a broad signal at δ 3.16 ppm and two doublet resonances with a coupling constant of 8.4 Hz each appeared at δ 1.29 and 1.19 ppm, respectively, due to the –CH hydrogen and isopropyl methyl hydrogen atoms of the imidazolin-2-imine fragment of ligand 1c. A sharp singlet at δ 0.09 ppm was also observed for the trimethylsilyl group present in complex 2c. In the 13C{1H} NMR spectra of 2b and 2c, the chemical shift of the central imidazole carbon was observed at 149.6 ppm for 2b (versus 146.7 ppm for 1b) and at 147.5 ppm for 2c (versus 150.5 ppm for 1c), while the carbonyl carbon nucleus resonated at δ 158.2 ppm for 2b (versus 154.2 ppm 1b) and at 165.2 ppm for 2c (versus 157.2 ppm for 1c). The decrease in the CO stretching frequency (νCO = 1623 cm−1 for 2b and 1620 cm−1 for 2c) compared to that of the urea ligands 1b (νCO = 1647 cm−1) and 1c (νCO = 1647 cm−1) also supported coordination through the oxygen atom.
X-ray quality crystals of complex 2b were grown at −35 °C by the slow liquid diffusion of THF into a concentrated toluene solution, while single crystals of 2c were obtained at −35 °C from a concentrated solution of toluene. Complex 2b crystallised in the tetragonal space group P21c, with two molecules of complex 2b and two THF solvent molecules in the unit cell. In contrast, complex 2c crystallised in the monoclinic space group P21/c, with four molecules of 2c in the unit cell.
Complex 2b is tetra-nuclear monomeric, whereas complex 2c is polymeric in nature. Details of the structural parameters are given in Table TS1 in the ESI.† The solid-state structure of complex 2b is shown in Fig. 2. This solid-state structure of the tetra-nuclear potassium complex 2b confirmed the κ2-coordination mode of each ligand fragment forming four times four-membered metallacycles. Each potassium is ligated with the imidazolium-2-iminato nitrogen and the oxygen atom of the isocyanate building block. Four potassium and four oxygen atoms formed a heterocubane structure, with an average K–O distance of 2.659–2.709 Å and a K–O–K angle between 80.37(8) and 89.15(8)°, thus confirming the distorted nature of the heterocubane motif, which can be best described as a K4 tetrahedron consisting of four oxygen atoms capping the four triangular faces (Fig. 3). Significant electron donation from the imidazolium ring to the ureate group is evident from the unusual elongation of the N1–C27 (1.411(5) Å) and N1–C1 [1.285(5) Å] bonds. In addition, both the bond lengths C27–O1 [1.279(4) Å] and C27–N4 [1.309(5) Å] are between those of carbon–oxygen and carbon–nitrogen single bonds and double bonds, respectively, thus indicating extensive electron delocalisation over N1–C27–O1. A similar observation was reported in [CpTiCl2(ImMesNCONTol)](Tol = p-tolyl) by Lavoie et al.11 They, however, reported a bi-dentate mode of coordination of the ureate ligand through the oxygen and nitrogen atoms of the isocyanate building block, while leaving the imidazolin-2-imine fragment uncoordinated. To the best of our knowledge, complex 2b is the first reported ureate–potassium complex where the mono-anionic ligand is coordinated through the oxygen atom of the ureate group and the nitrogen atom from the imidazolin-2-imine fragment. An even similar pattern of bonding was discussed by Snaith et al., although it must be noted that such a heterocubane structural motif, derived using an ureate ligand in alkali metal chemistry, has not been reported so far.17
The effect of a substituent over the imidazol ring is very significant. The solid-state structure of complex 2c was found to be polymeric in nature, due to the use of two equivalents of potassium precursor in its preparation compared to one equivalent used for the synthesis of 2b. The asymmetric unit of complex 2c is shown in Fig. 4. The molecular structure of 2c confirms the κ3 coordination of the ureate ligand towards potassium. It further reveals that two molecules [KN(SiMe3)2] are also present in the asymmetric unit in order to stabilise the complex 2c. The nitrogen atoms from the imidazolin-2-imine and the ureate fragments bond with the potassium ion K1, whereas the third donor atom oxygen is also ligated to another adjacent potassium ion that is attached to the bis(trimethyl)silyl amide group. Two four-membered metallacycles, N1–K1–N4–C28 and N7–K4–N10–C71, are formed by the chelation of two nitrogen atoms of each ureate ligand with the potassium ion, while two six–membered metallacycles, N4–C28–O1–K3–C30–C29 and N10–C71–O2–K2–C37–C72, are observed by the ligation of an oxygen atom and a phenyl carbon of each ureate ligand with the potassium ion. The phenyl ring of the isocyanate building block plays a key role in holding the two [(ImDippNCONPh)K] units through the bridging of two phenyl–carbon atoms. Thus, an additional two six–membered metallacycles, K1–N4–C29–C34–K2–N5 and K3–N6–K4–N10–C72–C73, are observed as a result of the coordination of the phenyl carbon and nitrogen from the bis(trimethyl)silyl amido fragment. Further units of the molecule grow from the ends of the potassium ions K3 and K4 to lead to complex 2c as a polymer. The bond distances in complex 2c (C1–N1 1.289 Å, C44–N7 1.283(6) Å, N1–C28 1.418(5) Å, N7–C71 1.418(5) Å, N4–C28 1.3276) Å, C71–N10 1.324 (6) Å, C28–O1 1.248(5) Å, C71–O2 1.255(6) Å) are in a range similar to those in complex 2b and indicate a significant electron delocalisation over N1–C28–N4 and N7–C71–N10. To the best of our knowledge, complex 2c is the first example where the monoanionic ureate ligand acts as the κ3 coordination mode using its three donor atoms. A similar polymeric potassium complex {([K(μ4-oMp)(THF)][K(μ3-oMP)])5}∞ (oMP = o-methyl phenol) was reported by Boyle and his co-workers.18 Due to the fluxional nature of the complex 2c, only one set of NMR signals was observed.
In the 1H NMR spectra of complex 3a measured in C6D6, the characteristic singlet at δ 6.28 ppm could be assigned to the olefinic protons of the imidazol backbone, which was in the same region (6.22 ppm) as that of ligand 1a. The tert-butyl methyl protons of the imidazol scaffold resonated at 1.46 ppm, whereas the tBu protons from the phenoxy ring were displayed as sharp singlets at 1.30 ppm. Additional singlet resonance at 2.10 ppm was obtained for the methyl protons located at position 4 of the phenoxy moiety. In the 13C spectra, resonances at 165.5 ppm for ipso carbon, 157.0 ppm for carbonyl carbon and 149.9 ppm for NCN group were observed for complex 3a.
Crystals of 3a were grown from a concentrated solution of toluene at −35 °C. Complex 3a crystallised in the asymmetric unit in the monoclinic space group P2/c along with a molecule of 1a. Details of the structural parameters are given in Table TS1 in the ESI.† The solid-state structure of the lithium fragment of complex 3a is shown in Fig. 5. The molecular structure clearly indicates that the neutral urea ligand 1a coordinated to the lithium ion in a κ1 mode through the oxygen atom of the isocyanate building block of the ligand. A four-membered Li2O2 diamond core was formed by the bridging coordination of two oxygen atoms from two phenoxy ligands. The terminal Li1–O1 bond distance [1.835(9) Å] where the oxygen atom is neutral is slightly shorter than the bridging Li–O2 bond (1.863(9) Å) where the oxygen atom is anionic. Dimeric lithium phenoxy complexes [(2,6-tBu2-4-Me-C6H2O)Li(THF)]2 and (2,6-tBu2-C6H2O)-Li(DMSO)]2, where one solvent (THF or DMSO) molecule is attached with each lithium centre to stabilise the respective complex, have been reported in the literature.19 Thus, the delocalisation of electrons over the N3–C12–O1 centres was observed in complex 3a. Furthermore, elongation of the C1–N3 bond [1.360(6) Å versus 1.346(3) Å for 1a] and the O1–C12 bond [1.270(6) Å versus 1.236(3) Å for 1a] also supports the above fact. It is assumed that the more nucleophilic lithium complex [ImtBuNCONPhLi] generated from 1a and LiCH2SiMe3 undergoes a protonolysis reaction with 2,6-di-tert-butyl-4-methyl phenol to form the neutral urea ligand and the lithium bis-phenoxo complex 3a. Thus, the neutral ligand 1a was trapped by and coordinated to the lithium ion, while another molecule of 1a remained uncoordinated in the asymmetric unit. Several hydrogen bonding interactions with the adjacent methyl protons from tBu groups with more electronegative oxygen atoms, important for the crystallisation of the compound (Fig. 5), were also observed in complex 3a.
The calcium potassium mixed metal complex 4a was isolated as a major product from a one-pot reaction with 1a and potassium precursor [KN(SiMe3)2] in a 1:3 molar ratio in THF, followed by the addition of one equivalent calcium diiodide at ambient temperature (Scheme 5). However, initial attempts to isolate the potassium free calcium iodo complex (1a)CaI(THF)n using the starting reagents in a 1:1:1 molar ratio did not meet success. The mixed Ca–K metal complex 4a was characterised using spectroscopic/analytic techniques and the molecular structure of 4a in its solid-state structure was established using single-crystal X-ray crystallography.
Complex 4a crystallised in the monoclinic space group P21/c, with four molecules in the unit cell. From the solid-state structure, it was evident that complex 4a was polymeric in nature. Details of the structural parameters are given in Table TS1 in the ESI;† the asymmetric unit of complex 4a is shown in Fig. 6, and the polymeric unit is given in Fig. 7. It is clearly seen in the asymmetric unit that two metal ions of calcium and potassium are, respectively, connected via μ2 bridging of the oxygen atom of the ureate ligand and the nitrogen atom from the bis(trimethylsilyl)amido group. This results in the four-fold coordinated central metal calcium ion adopting a distorted tetrahedral geometry due to the κ2 coordination of nitrogen and oxygen atoms from the isocyanate building block of ligand 1a while leaving the imidazolin-2-imine fragment uncoordinated. Two amido ligands bound the calcium ion to give two additional bonds. Thus, a four-membered metallacycle C1–O2–Ca1–N6 was formed to demonstrate the κ2 coordination of ligand 1a towards the calcium ion. The slight elongation of the C12–O1 bond [1.308(3) versus 1.236(3) Å for 1a] and the slight shortening of the C12–N4 bond [1.357(3) versus 1.389(3) Å] indicate an electron delocalisation over the O1–C12–N4 skeleton. The unperturbed bond distances of N1–C1 [1.338(3) versus 1.346(3) Å] and N1–C12 [1.342(3) versus 1.339(3) Å] are supportive of the non-interacting nature of the imidazolin-2-imine fragment towards ligation with both metal ions. In addition, a four-membered metallacycle O1–K1–N5–Ca1 was also formed. The bond distances Ca1–N4 [2.367(2) Å] and Ca1–O1 [2.355(2) Å] were similar to those [(2.4356(2) and 2.2805 (1) Å respectively] in the monomeric calcium ureate complex [(NacNac)Ca(η2-AdNC(NPh2)O](Ad = adamentyl) reported by Hill and co-workers.24 Similar mixed metal complexes with potassium–calcium, potassium–zinc, lithium–calcium and lithium–magnesium are reported in literature.25 The potassium ion K1 led the formation of the polymeric network by growing repetitive asymmetric units via η3 interactions with the phenyl ring of the adjacent ureate ligand fragment from another unit (Fig. 7). Such a polymeric network structure was realised due to the existence of multiple donor atoms in the ligand. In the NMR spectra of 4a, the presence of only one set of signals confirmed the fluxional nature of the complex.
The synthesis of complex 4a was performed as a one-pot reaction, followed by a crystallisation process. An undesired minor product 5a was also isolated from the re-crystallisation of the second crop solution after complex 4a had been separated. Complex 5a was characterised using NMR spectroscopy, and the solid-state structure of 5a was established by single-crystal X-ray diffraction analysis.
Complex 5a showed one set of signals in the 1H NMR spectra measured in C6D6. The resonances for the olefinic protons were obtained at δ 6.12 ppm as a singlet, whereas the sharp singlet at δ 1.42 ppm could be assigned to the tert-butyl group in the imidazol fragment. In addition, a sharp singlet for the trimethylsilyl groups was also observed at δ 0.43 ppm, thus confirming the presence of SiMe3 groups in the complex. The 13C{1H} NMR spectra was also within the expected range and very similar to that of complex 4a.
Complex 5a crystallised in the triclinic space group P, with one molecule in the unit cell. Details of the structural parameters are given in Table TS1 in the ESI,† and the asymmetric unit of complex 5a in its solid-state structure is shown in Fig. 8. The molecular structure is evidence of the incorporation of two fragments of dianionic disiloxane units [(Me2SiO)2O]2−, which bound three calcium ions in a bridging fashion. Three different chemical environments were observed for four calcium ions present in the molecule. The central calcium ion Ca1 was hexa-coordinated through the four oxygen atoms from two siloxane [(Me2SiO)2O]2− units and two oxygen atoms from two ureate ligands, resulting in the adoption of a distorted octahedral geometry around it. Each of the remaining two calcium ions had similar coordination spheres formed by the chelation of two μ3 oxygen atoms O1 and O2 of two siloxane [(Me2SiO)2O]2− units, and two nitrogen and two oxygen atoms of two monoanionic ureate ligands, resulting in the adoption of a distorted tetrahedral geometry around the calcium ion. Interestingly, for two ureate ligands, the nitrogen atoms from the isocyanate building block and the imidazolin-2-imine fragment alternatively bound either a calcium ion (Ca2) or a potassium ion (K2), thus making the ureate ligand a tridentate; the coordination mode can be best described as κ3 towards a metal ion. Apart from these calcium ions, the fourth calcium ion Ca3 exists as a [Ca{N(SiMe3)2}2] fragment in the molecule. Two kinds of potassium ions were also observed. The potassium ion K1 bound with two μ3 oxygen atoms (O1 and O2) from the two siloxane [(Me2SiO)2O]2− units and with two oxygen atoms (O3 and O4) from two isocyanate building blocks of the ureate ligand. Furthermore, a η6 attachment with an adjacent phenyl ring with a distance of (2.992–3.317 Å), which is quite common in potassium organometallic complexes, was also obtained.26 The second potassium atom K2, having one [N(SiMe3)2]− group attached, was coordinated by one imidazolin-2-imine nitrogen N3 along with a η6 arene interaction with the adjacent phenyl ring with a distance of (3.165–3.452 Å). Even the imidazol-2-iminato exocyclic C–N bond distances [N3–C24 1.342(6) Å and N6–C13 1.349(6) Å versus 1.346(3) Å for 1a] remained unchanged. The bond elongation of the ureate fragments [N3–C12 1.362(6) and N6–C11 1.391(6) Å versus 1.339(3) Å for 1a; C12–O4 1.299(6) and C11–O3 1.301(6) Å versus 1.236(3) Å for 1a] led to the conclusion that electron delocalisation occurs mainly on the N3–C12–O4 and N6–C11–O3 skeletons. The shortening of bonds C12–N7 1.341(6) and C11–N10 1.316(6) [versus 1.389(3) Å for 1a] indicated a localised carbon–nitrogen double bond rather than any involvement of electron delocalisation with the CO group. Thus, it can be assumed that compound 4a partly underwent decomposition with silicon grease under the reaction conditions so as to afford complex 5a. However, in a separate reaction, using a silicon-free grease, complex 4a was prepared without contamination from complex 5a. In complex 5a, the calcium ion Ca3 led to the repetition of the asymmetric unit, resulting in the growth of the polymeric chain.
1a: Yield 420 mg, 86%. 1H NMR (400 MHz, C6D6): δ 7.9 (br, 1H, HN), 7.81 (d, 3JH–H = 7.75 Hz, 2H, Ph), 7.18 (m, 2H, Ph), 6.83 (t, 3JH–H = 7.32 Hz, 1H, Ph), 6.18 (s, 2H, HCCH), 1.43 (s, 18 H, C(CH3)3) ppm. 13C{1H} NMR (100 MHz, C6D6): δ 158.8 (CO), 150.4 (NCN), 143.4 (Ar), 128.9 (Ar), 120.2 (Ar), 117.8 (Ar), 112.0 (HCCH), 58.4 (NC(CH3)3), 29.1 (C(CH)3) ppm. FTIR selected peaks (cm−1): 1627 (CO), 1574 (CN), 2979 (CH), 3155, 3287 (N–H). (C18H26N4O) (314.43) Calc. C 68.76, H 8.33, N 17.82; found C 68.23 H 8.11, N 17.59.
1b: Yield 515 mg, 75%. δ 7.09 (d, 3JHH = 7.88 Hz, 2H, Ph), 6.89 (m, 2H, Ph), 6.72 (s, 4H, m-CH(mesityl)), 6.62 (t, 3JHH = 7.48 Hz, 1H, Ph), 6.44 (br s, 1H, NH), 5.81 (s, 2H, HCCH), 2.26 (s, 12H, o-CH3(mesityl)), 2.05 (s, 6H, p-CH3(mesityl)) ppm. 13C{1H} NMR (100 MHz, C6D6): δ 158.0 (CO), 149.8 (ipso-Ar), 141.7 (NCN), 138.4 (ipso-Ph), 135.8 (o-Ar), 133.8 (p-Ar), 129.4 (m-Ar), 128.3 (o-Ph), 120.8 (p-Ph), 118.2 (m-Ph), 115.5 (HCCH), 21.0 (CH3), 18.2 (CH3) ppm. FTIR selected peaks (cm−1): 1580 (CN), 1647 (CO), 2916, 3211 (N–H). (C28H30N4O) (438.56) Calc. C 76.68, H 6.89, N 12.78; found C 76.31 H 6.39, N 12.29.
1c: Yield 506 mg, 78%. 1H NMR (400 MHz, C6D6): δ 7.22–7.20 (m, 4H, Ar), 7.12–7.10 (m, 2H, Ar), 6.98 (d, 3JHH = 8.72 Hz, 2H, Ph), 6.92–6.88 (m, 2H, Ph), 6.63 (t, 3JHH = 7.20 Hz, 1H, Ph), 6.10 (s, 2H, HCCH), 3.12 (sept, 3JHH = 6.80 Hz, 4H, CH(CH3)2), 1.45 (d, 3JHH = 6.80 Hz, 12H, CH(CH3)2), 1.16 (d, 3JHH = 6.80 Hz, 12H, CH(CH3)2) ppm. 13C{1H} NMR (100 MHz, C6D6): δ 157.1 (CO), 151.2 (NCN), 146.6 (ipso-Ar), 141.5 (ipso-Ph), 133.9 (o-Ar), 124.2 (o-Ph), 120.8 (p-Ph), 118.1 (m-Ph), 116.6 (HCCH), 29.2 (CH(CH3)2), 24.4 (CH(CH3)2), 23.7 (CH(CH3)2) ppm. FTIR selected peaks (cm−1): 1580 (CN), 1650 (CO), 2962, 3053, 3419 (N–H). (C34H42N4O) (522.72) Calc. C 78.12, H 8.10, N 10.72; found C 77.86, H 7.91, N 10.51.
Yield: 436 mg 86%. 1H NMR (400 MHz, C6D6): δ 7.80 (s, 1H, HN), 7.62 (d, 3JH–H = 7.84 Hz, 2H, Ph), 7.20 (m, 2H, Ph), 6.89 (t, 3JH–H = 7.32 Hz, 1H, Ph), 6.77 (s, 2H, HCCH), 1.63 (s, 18 H, C(CH)3) ppm. 13C{1H} NMR (100 MHz, C6D6): δ 178.2 (CO), 151.4 (ipso-Ph), 140.9 (NCN), 128.7 (Ph), 121.6 (Ph), 119.6 (Ph), 113.6 (HCCH), 58.5 (NC(CH3)3), 29.7 (C(CH3)3) ppm. FTIR selected peaks (cm−1): 1654 (CS), 1567 (CN), 2967, 3126, 3235 (N–H). (C18H26N4S) (330.49) Calc. C 65.42, H 7.93, N 16.95; found C 65.19 H 7.62, N 16.77.
Yield 141 mg, 65%. 1H NMR (400 MHz, C6D6): δ 7.12–7.08 (m, 2H, Ph), 6.94–6.84 (m, 3H, Ph), 6.73 (s, 4H, m-CH(mesityl)), 5.80 (s, 2H, HCCH), 3.57 (thf), 2.26 (s, 12H, CH3), 2.06 (s, 6H, CH3), 1.40 (thf) ppm. 13C{1H} NMR (100 MHz, C6D6): δ 158.2 (CO), 149.6 (NCN), 146.4 (ipso-Ar), 138.4 (ipso-Ph), 135.9 (o-Ar), 133.9 (Ph), 129.4 (Ph), 128.3 (Ar), 120.1 (Ph), 115.3 (HCCH), 20.9 (CH3), 18.2 (CH3) ppm. FTIR selected peaks (cm−1): 1623 (CO), 2956, 3078. (C128H148K N16O8) (2077.75) Calc. C 73.99, H 7.18, N 10.79; found C 73.54 H 6.94, N 10.32.
Yield 395 mg, 52%. 1H NMR (400 MHz, C6D6): δ 7.53 (m, 2H, Ar), 7.34 (m, 4H, Ar), 7.11 (m, 3H, Ph), 7.00 (m, 2H, Ph), 5.95 (s, 2H, HCCH), 3.16 (m, 4H, CH(CH3)2), 1.29 (d, 3JHH = 8.43 Hz, 12H, CH(CH3)2), 1.12 (d, 3JHH = 8.43 Hz 12H, CH(CH3)2), 0.09 (s, 18H, Si(CH3)3) ppm. 13C{1H} NMR (100 MHz, C6D6): δ 165.2 (CO), 147.5 (NCN), 135.8 (ipso-Ar), 135.3 (ipso-Ph), 129.3 (Ar), 127.8 (Ph), 120.6 (Ph), 125.7 (Ar), 123.8 (Ar), 115.4 (HCCH), 29.0 (CH(CH3)2), 24.7 (CH(CH3)2), 23.5 (CH(CH3)2) 2.65 (Si(CH3)3) ppm. FTIR selected peaks (cm−1): 1620 (CO), 2962, 3053. (C80H118K4N10O2Si4) (1520.61) Calc. C 63.19, H 7.82, N 9.21; found C 62.72 H 7.41, N 9.01.
Yield 335 mg, 62%. 1H NMR (400 MHz, C6D6): δ 7.57 (d, 3JH–H = 8.0 Hz, 2H, Ar), 7.22 (t, 3JH–H = 8.0 Hz, 2H, Ar), 7.02 (s, 2H, Ar), 6.85 (t, 3JH–H = 8.0 Hz, 1H, Ar), 6.28 (s, 2H, HCCH), 2.10 (6H, CH3), 1.46 (s, 18 H, C(CH3)3), 1.30 (18H, C(CH3)3) ppm. 13C{1H} NMR (100 MHz, C6D6): δ 165.5 (ipso –Ar), 157.0 (CO), 149.9 (NCN), 141.1 (Ar), 133.1 (Ar), 129.3 (Ar), 128.5 (Ar), 128.3 (Ar), 125.8 (Ar), 120.4 (Ar), 119.3 (Ar), 112.1 (HCCH), 58.6 (NC(Me)2), 33.8 (C(CH3)3), 32.6 (C(CH3)3), 32.3 (CH)3), 29.1 (C(CH)3) ppm. FTIR selected peaks (cm−1): 1627 (CO), 2980, 3155, 3297 (N–H). (C102H150Li2N16O6) (1710.27) Calc. C 71.63, H 8.84, N 13.10; found C 71.33 H 8.37, N 12.87.
Yield 426 mg, 57%. 1H NMR (400 MHz, C6D6): δ 7.80 (m, 2H, Ar), 7.29 (m, 3JH–H = 8.0 Hz, 2H, Ar)), 7.06 (m, 1H, Ar), 6.16 (s, 2H, HCCH), 3.42 (thf), 1.40 (thf), 1.49 (s, 18 H, C(CH3)3) 0.43 (s, 18H, Si(CH3)3), 0.21 (s, 18H, Si(CH3)3) ppm. 13C{1H} NMR (100 MHz, C6D6): δ 164.1 (CO), 152.7 (NCN), 129.5 (Ar), 129.1 (Ar), 128.1 (Ar), 127.2 (Ar), 123.9 (Ar), 119.2 (Ar), 111.6 (HCCH), 68.5 (NC(CH3)3), 57.8 (thf), 29.4 (C(CH3)3) 25.2 (thf), 6.16 (Si(CH3)3), 2.90 (Si(CH3)3) ppm. FTIR selected peaks (cm−1): 1619 (CO), 2954. (C33H64CaKN6OSi4) (752.42) Calc. C 52.68, H 8.57, N 11.17; found C 52.22 H 8.13, N 10.88.
5a: Compound 5a was obtained as a minor product from the second crop solution after the crystals of 4a were isolated. Yield 195 mg, 8%. 1H NMR (400 MHz, C6D6): δ 7.81–7.68 (m, 2H, Ar), 7.31–7.27 (m, 2H, Ar)), 7.14–7.08 (m, 1H, Ar), 6.12 (s, 2H, HCCH), 3.57 (thf), 1.45 (thf), 1.42 (s, 18 H, C(CH3)3) 0.43 (s, 18H, Si(CH3)3), 0.21 (s, 18H, Si(CH3)3) 0.09 (s, 24H, OSi(CH3)2) ppm. 13C{1H} NMR (100 MHz, C6D6): δ 168.1 (CO), 156.3 (NCN), 129.8 (Ar), 129.3 (Ar), 128.0 (Ar), 127.6 (Ar), 125.1 (Ar), 120.2 (Ar), 115.4 (HCCH), 66.5 (NC(CH3)3), 57.8 (thf), 28.4 (C(CH3)3) 25.2 (thf), 7.15 (Si(CH3)3), 3.76 (Si(CH3)3), 1.02 (OSi(CH3)2) ppm. FTIR selected peaks (cm−1): 1672 (CO), 2956. (C118H212Ca5 K4N20O10Si12) (2764.96) Calc. C 51.26, H 7.73, N 10.13; found C 50.94 H 7.34, N 9.79.
Footnote |
† Electronic supplementary information (ESI) available: For crystallographic details in CIF. CCDC 1046050–1046056. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5dt00490j |
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