Codelivery of nitric oxide (NO) and drugs based on a single nanocarrier is a promising therapeutic strategy. Here, we report a one-step nanoprecipitation method to generate nanoparticles that possess simultaneous NO-donating and doxorubicin releasing properties. S-Nitroso polysilsesquioxane acts like an avid “drug sponge” that attracts drug molecules into nanospheres.
M. Wang, S. Chiu, H. Chou and T. Hu, Chem. Commun., 2015, 51, 15649 DOI: 10.1039/C5CC06087G
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