A FRET–ICT dual-quenching fluorescent probe with large off–on response for H2S: synthesis, spectra and bioimaging

Changyu Zhang; Lv Wei; Chao Wei; Jie Zhang; Runyu Wang; Zhen Xi; Long Yi

doi:10.1039/C5CC01184A

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A FRET–ICT dual-quenching fluorescent probe with large off–on response for H₂S: synthesis, spectra and bioimaging†

Changyu Zhang,‡^a Lv Wei,‡^bc Chao Wei,^bc Jie Zhang,^a Runyu Wang,^bc Zhen Xi*^bc and Long Yi*^ac

Author affiliations

* Corresponding authors

^a Beijing Key Laboratory of Bioprocess and College of Chemical Engineering, Beijing University of Chemical Technology, Beijing 100029, China
E-mail: yilong@mail.buct.edu.cn

^b State Key Laboratory of Elemento-Organic Chemistry and Department of Chemical Biology, National Pesticide Engineering Research Center (Tianjin), Nankai University, Tianjin 300071, China
E-mail: zhenxi@nankai.edu.cn
Tel: +86 22 23504782

^c Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin 300071, China

Abstract

A FRET–ICT dual-quenching probe with large off–on fluorescent response upon H₂S treatment is reported. The probe can be used for bioimaging of endogenous H₂S in living cells.

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Article information

DOI: https://doi.org/10.1039/C5CC01184A
Article type: Communication
Submitted: 08 Feb 2015
Accepted: 24 Mar 2015
First published: 24 Mar 2015

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Chem. Commun., 2015,51, 7505-7508

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A FRET–ICT dual-quenching fluorescent probe with large off–on response for H₂S: synthesis, spectra and bioimaging

C. Zhang, L. Wei, C. Wei, J. Zhang, R. Wang, Z. Xi and L. Yi, Chem. Commun., 2015, 51, 7505 DOI: 10.1039/C5CC01184A

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Chemical Communications