Issue 37, 2015
From the journal:

Chemical Communications

pH-Sensitive gold nanoclusters: preparation and analytical applications for urea, urease, and urease inhibitor detection†

Hao-Hua Deng,ab   Gang-Wei Wu,ac   Zhi-Qiang Zou,ab   Hua-Ping Peng,ab   Ai-Lin Liu,ab   Xin-Hua Lin,ab   Xing-Hua Xiad  and  Wei Chen*ab  

* Corresponding authors

a Department of Pharmaceutical Analysis, Fujian Medical University, Fuzhou 350004, China
E-mail: chenandhu@163.com

b Nano Medical Technology Research Institute, Fujian Medical University, Fuzhou 350004, China

c Department of Pharmacy, Fujian Provincial Hospital, Fuzhou 350001, China

d State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China

Abstract

Herein, we reported for the first time a facile synthetic process of gold nanoclusters (AuNCs) by using N-acetyl-L-cysteine both as a reducing agent and as a protection ligand. Based on the pH stimuli-responsive properties of the as-prepared AuNCs, we constructed a pH-sensing platform for the detection of urea, urease, and urease inhibitors.

Graphical abstract: pH-Sensitive gold nanoclusters: preparation and analytical applications for urea, urease, and urease inhibitor detection

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Article information

DOI
https://doi.org/10.1039/C5CC00702J
Article type
Communication
Submitted
25 Jan 2015
Accepted
30 Mar 2015
First published
30 Mar 2015

Chem. Commun., 2015,51, 7847-7850

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pH-Sensitive gold nanoclusters: preparation and analytical applications for urea, urease, and urease inhibitor detection

H. Deng, G. Wu, Z. Zou, H. Peng, A. Liu, X. Lin, X. Xia and W. Chen, Chem. Commun., 2015, 51, 7847 DOI: 10.1039/C5CC00702J

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