Ke Quan, Jin Huang, Xiaohai Yang, Yanjing Yang, Le Ying, He Wang, Yong He and Kemin Wang
Chem. Commun., 2015,51, 937-940
DOI:
10.1039/C4CC08488H,
Communication
Here we introduce an enzyme-free and colorimetric detection strategy for small molecule adenosine. The approach is based on the adenosine–aptamer binding triggered liberation of an initiator strand that consecutively catalyzes DNA hairpins hybridized from singles to couples. These couples induce gold nanoparticles assembled via crosslinking, which could be visualized by a color change.
