Issue 25, 2015

A multi-ligation strategy for the synthesis of heterofunctionalized glycosylated scaffolds

Abstract

Well-defined heterofunctionalized glycosylated scaffolds with unprecedented molecular combinations have been prepared using up to five different bioorthogonal ligations. This approach opens up chemical access to a diversity of biomolecular structures with high biological potential.

Graphical abstract: A multi-ligation strategy for the synthesis of heterofunctionalized glycosylated scaffolds

Supplementary files

Article information

Article type
Communication
Submitted
15 Jul 2014
Accepted
08 Aug 2014
First published
11 Aug 2014

Chem. Commun., 2015,51, 5436-5439

Author version available

A multi-ligation strategy for the synthesis of heterofunctionalized glycosylated scaffolds

B. Thomas, M. Fiore, G. C. Daskhan, N. Spinelli and O. Renaudet, Chem. Commun., 2015, 51, 5436 DOI: 10.1039/C4CC05451B

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