Issue 46, 2014
From the journal:

RSC Advances

Mitigating UVA light induced reactivity of 6-thioguanine through formation of a Ru(ii) half-sandwich complex†

Raja Mitraa  and  Ashoka G. Samuelson*a  

* Corresponding authors

a Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore 560012, India
E-mail: ashoka@ipc.iisc.ernet.in
Fax: +91-80-23601552
Tel: +91-80-22932663

Abstract

The organometallic complex of (η6-cymene)Ru(II)Br with 6-thioguanine (6-TG) shows better photostability than the biologically active 6-thioguanine which is used as an immunosuppressant and as an anticancer agent.

Graphical abstract: Mitigating UVA light induced reactivity of 6-thioguanine through formation of a Ru(ii) half-sandwich complex

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Article information

DOI
https://doi.org/10.1039/C4RA02960G
Article type
Communication
Submitted
23 Apr 2014
Accepted
27 May 2014
First published
27 May 2014

RSC Adv., 2014,4, 24304-24306

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Mitigating UVA light induced reactivity of 6-thioguanine through formation of a Ru(II) half-sandwich complex

R. Mitra and A. G. Samuelson, RSC Adv., 2014, 4, 24304 DOI: 10.1039/C4RA02960G

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