Shital K. Chattopadhyay, Indranil Kundu and Ratnava Maitra
Org. Biomol. Chem., 2014,12, 8087-8093
DOI:
10.1039/C4OB01360C,
Paper
Thermally induced cascade sigmatropic rearrangement of a butynyloxycoumarin derivative has led to a quick access to the coumarin–pterocarpan hybrid molecule. Biophysical studies together with molecular modeling show that this nature-inspired hybrid molecule is capable of binding to the minor groove of DNA as a non-conventional entity.