Issue 92, 2014
From the journal:

Chemical Communications

Colorimetric detection of human chorionic gonadotropin using catalytic gold nanoparticles and a peptide aptamer†

Chia-Chen Chang, ORCID logo a   Chie-Pein Chen,b   Chung-Han Lee,a   Chen-Yu Chen*bcd  and  Chii-Wann Lin*aef  

* Corresponding authors

a Institute of Biomedical Engineering, National Taiwan University, Taipei 106, Taiwan
E-mail: cwlinx@ntu.edu.tw

b Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei 104, Taiwan
E-mail: f122481@mmh.org.tw
Fax: +886-2-23620586
Tel: +886-2-33665271

c Mackay Junior College of Medicine, Nursing, and Management, Taipei 112, Taiwan

d Mackay Medical College, Taipei 252, Taiwan

e Institute of Biomedical Electronic and Bioinformatics, National Taiwan University, Taipei 106, Taiwan

f Center for Emerging Material and Advanced Devices, National Taiwan University, Taipei 106, Taiwan

Abstract

We combined catalytic gold nanoparticles (AuNPs) with an hCG-specific peptide aptamer to create a simple, sensitive, label-free colorimetric assay for hCG. The applications of this colorimetric biosensor may be expanded by changing the peptide aptamer.

Graphical abstract: Colorimetric detection of human chorionic gonadotropin using catalytic gold nanoparticles and a peptide aptamer

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Article information

DOI
https://doi.org/10.1039/C4CC06366J
Article type
Communication
Submitted
13 Aug 2014
Accepted
01 Oct 2014
First published
01 Oct 2014

Chem. Commun., 2014,50, 14443-14446

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Colorimetric detection of human chorionic gonadotropin using catalytic gold nanoparticles and a peptide aptamer

C. Chang, C. Chen, C. Lee, C. Chen and C. Lin, Chem. Commun., 2014, 50, 14443 DOI: 10.1039/C4CC06366J

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