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Rh-MoOx/SiO2 is an effective heterogeneous catalyst for selective hydrogenation of amino acids to amino alcohols in a water solvent. MoOx modification of Rh drastically enhanced the activity and improved the selectivity and ee. Various amino alcohols were obtained in high yields (90–94%) with complete retention of configuration.

Graphical abstract: Catalytic hydrogenation of amino acids to amino alcohols with complete retention of configuration

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