Benjamin L. Alford and Helmut M. Hügel
Org. Biomol. Chem., 2013,11, 2724-2727
DOI:
10.1039/C3OB27478K,
Paper
The total synthesis of a methylated analogue of (+)-Salvianolic acid C has been achieved. Key aspects of the synthetic route include an economical Cu(I) acetylide coupling, unique carboxyl activation conditions via microwave irradiation and a novel lipase catalysed kinetic resolution of a racemic mixture of