Yang Gao, Wanqing Wu, Huawen Huang, Yubing Huang and Huanfeng Jiang
Chem. Commun., 2014,50, 846-848
DOI:
10.1039/C3CC47310D,
Communication
A novel and efficient Pd-catalyzed intermolecular [3 + 2] carbocyclization of alkynols and electron-deficient alkynes for the synthesis of halo-cyclopentadienes (Cps) has been developed. The present protocol employs simple propargyl alcohols as the C3 group to participate in the cyclization reaction, providing a highly convenient and atom-economical entry to the halo-cyclopentadiene framework.
![Graphical abstract: Palladium-catalyzed intermolecular [3 + 2] carbocyclization of alkynols and propiolates: an efficient entry to halo-cyclopentadienes](/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=C3CC47310D "Graphical abstract")
