Silver-catalyzed oxidative coupling/cyclization of acrylamides with 1,3-dicarbonyl compounds†
Abstract
An efficient silver-catalyzed oxidative cyclization of acrylamides with 1,3-dicarbonyl compounds is described. It proceeds through a tandem radical addition/cyclization process, in which two new C–C bonds were formed. Furthermore, the same concept can also be extended to the reaction of easily available ketones and acrylamides.