Naresh K. Mani, Sergii Rudiuk and Damien Baigl
Chem. Commun., 2013,49, 6858-6860
DOI:
10.1039/C3CC44016H,
Communication
A DNA molecule is rotated under a transversal electric field to be perpendicular to a longitudinal, multicomponent microfluidic flow. Positioning the interface allows us to control DNA unzipping with spatio-temporal resolution. This demonstrates that a microfluidic gradient can be applied at the single molecule level for a dynamic intramolecular stimulation.