Issue 39, 2013
From the journal:

Chemical Communications

Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family†‡

Julia Arens,ab   Benedikt Engels,c   Stephan Klopries,a   Stefan Jennewein,c   Christian Ottmannd  and  Frank Schulz*ab  

* Corresponding authors

a Technische Universität Dortmund, Otto-Hahn-Straße 6, 44227 Dortmund, Germany
E-mail: frank3.schulz@tu-dortmund.de
Fax: +49 231 133-2498
Tel: +49 231 133-2429

b Max Planck Institut für molekulare Physiologie, Otto-Hahn-Straße 11, 44227 Dortmund, Germany

c Fraunhofer-Institut für Molekularbiologie und angewandte Ökologie, Forckenbeckstraße 6, 52074 Aachen, Germany

d Chemical Genomics Centre, Otto-Hahn-Straße 15, 44227 Dortmund, Germany

Abstract

Herein preparative scale access to the shared precursor of the fusicoccane family of diterpenoids through biosynthesis in three different microbial hosts is reported. A method to purify the metabolite in high purity and on a preparative scale was explored.

Graphical abstract: Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family

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Article information

DOI
https://doi.org/10.1039/C2CC37154E
Article type
Communication
Submitted
01 Oct 2012
Accepted
17 Dec 2012
First published
07 Jan 2013

Chem. Commun., 2013,49, 4337-4339

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Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family

J. Arens, B. Engels, S. Klopries, S. Jennewein, C. Ottmann and F. Schulz, Chem. Commun., 2013, 49, 4337 DOI: 10.1039/C2CC37154E

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