The nonribosomal synthesis of diketopiperazines in tRNA-dependent cyclodipeptide synthase pathways
Abstract
Covering: up to 2012
We review here work on the biosynthesis of diketopiperazines (DKPs), a large class of natural products with noteworthy biological activities, focusing on the biosynthetic pathways involving cyclodipeptide synthases (CDPSs), a newly defined family of enzymes. Distinct from nonribosomal