Issue 10, 2012

Leveraging kinase inhibitors to develop small molecule tools for imaging kinases by fluorescence microscopy

Abstract

As the usage of fluorescence microscopy as a tool to study biological systems continues to grow, so does the need for additional tools that permit the selective detection of proteins of interest. Existing selective and well-characterized kinase inhibitors may be exploited to develop novel small molecule probes useful in imaging kinases by fluorescence microscopy.

Graphical abstract: Leveraging kinase inhibitors to develop small molecule tools for imaging kinases by fluorescence microscopy

Supplementary files

Article information

Article type
Communication
Submitted
16 Mar 2012
Accepted
10 May 2012
First published
10 May 2012

Mol. BioSyst., 2012,8, 2523-2526

Leveraging kinase inhibitors to develop small molecule tools for imaging kinases by fluorescence microscopy

Z. Zhang, N. Kwiatkowski, H. Zeng, S. M. Lim, N. S. Gray, W. Zhang and P. L. Yang, Mol. BioSyst., 2012, 8, 2523 DOI: 10.1039/C2MB25099C

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