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A highly chemo-, regio-selective, and efficient palladium-catalyzed deamidative arylation of azoles with arylamides, as an aryl metal equivalent, has been developed. The reaction proceeds smoothly to generate the corresponding products in good yields via a tandem decarbonylation–C–H activation.

Graphical abstract: Palladium-catalyzed deamidative arylation of azoles with arylamides through a tandem decarbonylation–C–H functionalization

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