Issue 24, 2011
From the journal:

Chemical Communications

Novel dipolarophiles and dipoles in the metal-catalyzed enantioselective 1,3-dipolar cycloaddition of azomethine ylides

Javier Adrio*a  and  Juan C. Carretero*a  

* Corresponding authors

a Departamento de Química Orgánica, Facultad de Ciencias, Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain
E-mail: javier.adrio@uam.es, juancarlos.carretero@uam.es
Fax: +34 914973966

Abstract

The catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides constitutes one of the most powerful and atom economical methods for the enantioselective construction of pyrrolidines. This article highlights the recent developments in this area, with special focus on contributions improving the structural scope at the dipolarophile and azomethine ylide partners.

Graphical abstract: Novel dipolarophiles and dipoles in the metal-catalyzed enantioselective 1,3-dipolar cycloaddition of azomethine ylides

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Article information

DOI
https://doi.org/10.1039/C1CC10779H
Article type
Feature Article
Submitted
10 Feb 2011
Accepted
15 Mar 2011
First published
06 Apr 2011

Chem. Commun., 2011,47, 6784-6794

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Novel dipolarophiles and dipoles in the metal-catalyzed enantioselective 1,3-dipolar cycloaddition of azomethine ylides

J. Adrio and J. C. Carretero, Chem. Commun., 2011, 47, 6784 DOI: 10.1039/C1CC10779H

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