Issue 44, 2005

Total synthesis of aspercyclide C

Abstract

The first total synthesis of (+)-aspercyclide C (1) is reported using a kinetically controlled RCM reaction to form the 11-membered, unsaturated lactone ring of this bioactive diaryl ether macrolide.

Graphical abstract: Total synthesis of aspercyclide C

Supplementary files

Article information

Article type
Communication
Submitted
14 Sep 2005
Accepted
28 Sep 2005
First published
17 Oct 2005

Chem. Commun., 2005, 5583-5585

Total synthesis of aspercyclide C

A. Fürstner and C. Müller, Chem. Commun., 2005, 5583 DOI: 10.1039/B512877C

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