β-Depsipeptides—the effect of a missing and a weakened hydrogen bond on the stability of the β-peptidic 314-helix

Dieter Seebach; Yogesh R. Mahajan; Ramanathan Senthilkumar; Magnus Rueping; Bernhard Jaun

doi:10.1039/B204187C

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

β-Depsipeptides—the effect of a missing and a weakened hydrogen bond on the stability of the β-peptidic 3₁₄-helix†

Dieter Seebach,*^a Yogesh R. Mahajan,‡^a Ramanathan Senthilkumar,^a Magnus Rueping ‡^a and Bernhard Jaun*^a

Author affiliations

* Corresponding authors

^a Laboratorium für Organische Chemie der Eidgenössischen Technischen Hochschule, ETH-Hönggerberg, Wolfgang-Pauli-Strasse 10, Zürich, Switzerland
E-mail: seebach@org.chem.ethz.ch
Fax: +4116321144
Tel: +416322990

Abstract

The importance of hydrogen bonding in β-peptide 3₁₄-helices is demonstrated by an NMR analysis of three β-heptadepsipeptides containing a 3-hydroxybutanoic residue in position 2, 4 or 6.

Download options Please wait...

Supplementary files

NMR and NOE data DOC (376K)

Article information

DOI: https://doi.org/10.1039/B204187C
Article type: Communication
Submitted: 30 Apr 2002
Accepted: 12 Jun 2002
First published: 26 Jun 2002

Download Citation

Chem. Commun., 2002, 1598-1599

Permissions

Request permissions

β-Depsipeptides—the effect of a missing and a weakened hydrogen bond on the stability of the β-peptidic 3₁₄-helix

D. Seebach, Y. R. Mahajan, R. Senthilkumar, M. Rueping and B. Jaun, Chem. Commun., 2002, 1598 DOI: 10.1039/B204187C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications