Issue 2, 2002
From the journal:

Chemical Communications

Lipophilic derivatives of cyclam as new inhibitors of tumor cell growth

John W. Sibert,*a   Ann H. Coryb  and  Joseph G. Cory*b  

* Corresponding authors

a Department of Chemistry, The University of Texas at Dallas, P.O. Box 830688, Richardson, TX, USA
E-mail: sibertj@utdallas.edu

b Department of Biochemistry, East Carolina University, Brody School of Medicine, Greenville, NC, USA
E-mail: coryjo@mail.ecu.edu

Abstract

Two new lipophilic tetraazamacrocycles were prepared and, in contrast to non-lipophilic analogs, found to be potent inhibitors of tumor cell growth in vitro with IC50 values below 10 micromolar.

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Article information

DOI
https://doi.org/10.1039/B107899M
Article type
Communication
Submitted
10 Aug 2001
Accepted
12 Dec 2001
First published
10 Jan 2002

Chem. Commun., 2002, 154-155

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Lipophilic derivatives of cyclam as new inhibitors of tumor cell growth

J. W. Sibert, A. H. Cory and J. G. Cory, Chem. Commun., 2002, 154 DOI: 10.1039/B107899M

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