Issue 17, 2001

Is N-acetylornithine aminotransferase the real N-succinyl-ll-diaminopimelate aminotransferase in Escherichia coli and Mycobacterium smegmatis?

Abstract

We examined the similarities and differences between the activities of N-succinyl-LL-diaminopimelate aminotransferase (DAP-AT) and N-acetylornithine aminotransferase (NAcO-AT) from E. coli and M. smegmatis in order to investigate recent claims that the two enzymes are one and the same. The results do not support the hypothesis that the two activities are catalysed by a single enzyme.

Graphical abstract: Is N-acetylornithine aminotransferase the real N-succinyl-ll-diaminopimelate aminotransferase in Escherichia coli and Mycobacterium smegmatis?

Article information

Article type
Communication
Submitted
11 Jul 2001
Accepted
31 Jul 2001
First published
10 Aug 2001

J. Chem. Soc., Perkin Trans. 1, 2001, 2006-2008

Is N-acetylornithine aminotransferase the real N-succinyl-LL-diaminopimelate aminotransferase in Escherichia coli and Mycobacterium smegmatis?

R. J. Cox and P. S. H. Wang, J. Chem. Soc., Perkin Trans. 1, 2001, 2006 DOI: 10.1039/B106146C

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