Issue 3, 2001

Unexpected synthesis of 3,5-diethoxycarbonyl-2-pentafluorophenyl-4-phenyl-7,8,9,10-tetrafluoro-4,5-dihydrobenzo[b]oxacin-6-one

Abstract

The reaction of ethyl pentafluorobenzoylacetate with benzaldehyde in the presence of a base affords 3,5-diethoxycarbonyl-2-pentafluorophenyl-4-phenyl-7,8,9,10-tetrafluoro-4,5-dihydrobenzo[b]oxacin-6-one in contrast to fluoroalkyl-containing 3-oxo esters yielding 3,5-dialkoxycarbonyl-2,6-dihydroxy-2,6-difluoroalkyl-4-phenyltetrahydropyranes under the same conditions.

Article information

Article type
Paper

Mendeleev Commun., 2001,11, 119-120

Unexpected synthesis of 3,5-diethoxycarbonyl-2-pentafluorophenyl-4-phenyl-7,8,9,10-tetrafluoro-4,5-dihydrobenzo[b]oxacin-6-one

Y. V. Burgart, M. V. Pryadeina, O. G. Kuzueva, M. I. Kodess, V. I. Saloutin and O. N. Chupakhin, Mendeleev Commun., 2001, 11, 119 DOI: 10.1070/MC2001v011n03ABEH001398

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