Issue 17, 2000
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

An activated phosphate for an efficient amide and peptide coupling reagent

Tomohisa Yasuhara,a   Yasuo Nagaokaa  and  Kiyoshi Tomioka*a  

* Corresponding authors

a Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan

Abstract

Activation of diethyl phosphate was realized by attaching trifluoromethanesulfonanilide as an efficient leaving group and the phosphate 1 proved to be a promising amide and peptide coupling reagent.

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Article information

DOI
https://doi.org/10.1039/B004264L
Article type
Communication
Submitted
30 May 2000
Accepted
02 Aug 2000
First published
15 Aug 2000

J. Chem. Soc., Perkin Trans. 1, 2000, 2901-2902

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An activated phosphate for an efficient amide and peptide coupling reagent

T. Yasuhara, Y. Nagaoka and K. Tomioka, J. Chem. Soc., Perkin Trans. 1, 2000, 2901 DOI: 10.1039/B004264L

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