Synthesis of α-bromo-β-lactam via a novel catalytic Hunsdiecker like protocol † ‡

Abstract

While α,β-unsaturated aromatic carboxylic acids, upon treatment with NBS and catalytic group-1 metal acetates, gives β-bromostyrenes, the corresponding reactions of α,β-unsaturated aromatic amides lead to α-bromo-β-lactams.

References

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