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DOI: 10.1039/A900375D (Paper) Reference Section for: J. Chem. Soc., Perkin Trans. 1, 1999, 1743-1754

Parasite glycoconjugates. Part 9.1 Synthesis of dec-9-enyl β-D-galactopyranosyl-(1→4)-α-D-mannopyranosyl phosphate and its epimers at the D-galactose moiety, substrate analogues for the elongating α-D-mannopyranosylphosphate transferase in the Leishmania

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Irina A. Ivanova, Andrew J. Ross, Michael A. J. Ferguson and Andrei V. Nikolaev

Abstract

A set of phosphodisaccharides, substrate analogues, which will be used to study the acceptor substrate specificity of the Leishmania biosynthetic enzymes, have been synthesized using the trichloroacetimidate method for the glycosylation reactions, SN2 nucleophilic displacement of triflic esters for epimerization and the glycosyl hydrogenphosphonate method for phosphorylation.

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