Highly efficient C-8 oxidation of substituted xanthines with substitution at the 1-, 3-, and 7- positions using biocatalysts

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K. M. Madyastha and G. R. Sridhar


Abstract

A bacterial consortium consisting of strains belonging to the genus Klebsiella and Rhodococcus quantitatively converts 1-, 3- and 7-substituted xanthines to their respective 8-oxo compounds.


References

  1. C. E. Cross, B. Halliwell, E. T. Borish, W. A. Phror, B. N. Ames, R. Saul, J. M. McCord and D. Harman, Ann. Intern. Med., 1987, 107, 526 Search PubMed.
  2. R. A. Floyd, Carcinogenesis, (London), 1990, 11, 1447 Search PubMed.
  3. R. W. Park, J. F. Holland and A. Jenkins, Cancer Res., 1962, 22, 469 CAS.
  4. Y. Nishida, J. Pharm. Pharmacol., 1991, 43, 885 Search PubMed.
  5. B. N. Ames, R. Cathcart, E. Schwiers and P. Hochstein, Proc. Natl. Acad. Sci. USA, 1981, 78, 6858 CAS.
  6. J. Meadows and R. C. Smith, Arch. Biochem. Biophys., 1986, 246, 838 CrossRef.
  7. A. M. Cohen, R. E. Aberdroth and P. Hochstein, FEBS Lett., 1984, 174, 147 CrossRef CAS.
  8. K. J. Kittridge and R. L. Wilson, FEBS Lett., 1984, 170, 162 CrossRef CAS.
  9. M. G. Simic and S. V. Jovanovic, J. Am. Chem. Soc., 1989, 111, 5778 CrossRef CAS.
  10. K. Yoshiyuki, S. Tetsuo and S. Keiko, Jpn. Kokai Tokkyo Koho, 1989, JP O1,275,511 Search PubMed; Chem. Abstr., 1990, 112, 204482z Search PubMed.
  11. K. Yoshiyuki, N. Toru, N. Shiro, Y. Koichi and Y. Kyoko, Jpn. Kokai Tokkyo Koho, 1989, JP O1,299,229 Search PubMed; Chem. Abstr., 1990, 113, 172035h Search PubMed.
  12. R. Saladino, C. Crestini, R. Bernini, E. Mincione and R. Ciafrino, Tetrahedron Lett., 1995, 36, 2665 CrossRef CAS.
  13. Y. Kitade, Y. Takeda, R. Hirota and Y. Maki, Tetrahedron Lett., 1995, 36, 2633 CrossRef CAS.
  14. J. L. Ferrero and A. H. Neims, Life Sci., 1983, 33, 1173 CrossRef CAS.
  15. J. M. Porter, B. S. Cutler, B. Y. Lee, T. Reich, F. A. Reichle, J. T. Scogin and D. E. Strandness, Am. Heart J., 1982, 104, 66 CAS.
  16. C. G. A. Persson and G. Kjellin, Acta. Pharmacol. Toxicol., 1981, 49, 313 Search PubMed.
  17. I. Goldberg and C. L. Cooney, Appl. Environ. Microbiol., 1981, 41(1), 148 CAS.
  18. J. E. Makins, G. Holt and K. D. Macdonald, J. Gen. Microbiol., 1980, 119, 397 Search PubMed.
  19. W. Pfleiderer, Liebigs Ann. Chem., 1974, 2030 Search PubMed.
  20. G. S. Rao, K. L. Khanna and H. H. Cornish, J. Pharm. Sci., 1972, 61(11), 1822 CAS.
  21. B. P. Cho and F. E. Evans, Nucleic Acid Res., 1991, 19(5), 1041 Search PubMed.
  22. S. Zbaida, R. Kariv, P. Fischer and D. Gilhar, Xenobiotica, 1987, 17(5), 617 CAS.
  23. C. A. Woolfolk and J. S. Downard, J. Bacteriol., 1978, 135, 422 CAS.
  24. Y. Machida and T. Nakanishi, Agric. Biol. Chem, 1981, 45(2), 425 CAS.
  25. W. V. Yikang and Per Ahlberg, Synthesis, 1994, 463.
  26. Vögel's Text book of Practical Organic Chemistry, 5th edition, eds. B. S. Furniss, A. J. Hannaford, P. W. G. Smith and A. R. Tatchell, Longman Publishers Pvt. Ltd, UK, 1989 Search PubMed.
  27. C. Wang, J. Wang and C. Chan, Bull. Inst. Chem., Acad. Sin., 1981, 28, 69 Search PubMed.
  28. J. W. Daly, W. L. Padgett and M. T. Shamim, J. Med. Chem., 1982, 25, 197 CrossRef CAS.
  29. W. Seubert, J. Bacteriol., 1960, 79, 426 CAS.
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