DOI: 10.1039/A904499J
(Paper)
Reference Section for: J. Chem. Res. (S), 1999, 606-607
Stereoselective Synthesis of Flavonoids. Part 8. Free Phenolic Flavan-3-ol Diastereoisomers
(Note: The full text of this document is currently only available in the PDF Version )
Reinier J. J. Nel, Hendrik van Rensburg, Pieter S. van Heerden and Daneel Ferreira
Abstract
Asymmetric dihydroxylation of a series of poly-O-methoxymethyl-1,3-diarylpropenes with AD-mix-α or AD-mix-β and subsequent acid-catalyzed cyclization of the intermediate syn-diols permits the first synthetic access to all four diastereoisomers of free phenolic flavan-3-ols in high enantiomeric excess and yield.
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