A Novel 4α-Methyl Sterol from the Soft Coral Nephthea chabroli

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G. Mehta, Y. Venkateswarlu, M. Rama Rao and R. Uma


Abstract

A new sterol, 4α-methyl-24-methylene-5α-cholestan-3β,8β-diol (1) and three known sterols 4α-methyl-24-methylenecholestan-3β-ol, 4α-methylcholestan-3β-ol and 24-methylenecholest-4-en-3-one are isolated from the soft coral Nephthea chabroli and characterized through spectral data and in the case of 1 by X-ray crystallographic analysis.


References

  1. L. J. Goad, in Marine Natural Products: Chemical and Biological Perspectives, ed. P. J. Scheuer, Academic Press, New York, 1978, ch. 11, p. 75 Search PubMed.
  2. M. V. D'Auria, L. Minale and R. Riccio, Chem. Rev., 1993, 93, 1839 CrossRef CAS.
  3. J. C. Coll, Chem. Rev., 1992, 92, 613 CrossRef CAS.
  4. D. J. Faulkner, Nat. Prod. Rep., 1998, 15, 113 RSC and refs. therein.
  5. W. C. M. C. Kokke, L. Bohlin, W. Fenical and C. Djerassi, Phytochemistry, 1982, 21, 881 CrossRef CAS.
  6. M. S. Younus and C. Djerassi, Tetrahedron, 1974, 30, 4095 CrossRef CAS.
  7. J. W. Blunt and J. B. Stothers, Org. Magn. Reson., 1977, 9, 439 CrossRef CAS.
  8. M. Bortolotto, J. C. Braekman, D. Daloze, B. Tursch and R. Karlson, Steroids, 1977, 30, 159 CrossRef CAS.
  9. C. K. Johnson, ORTEP II, Report ORNL-5138, Oak Ridge National Laboratory, Oak Ridge, TN, 1976.
  10. W. C. M. C. Kokke, W. Fenical and C. Djerassi, Phytochemistry, 1981, 20, 127 CrossRef CAS.
  11. S. Gunasekera, S. Cranick and R. E. Longley, J. Nat. Prod., 1989, 52, 757 CrossRef CAS.
  12. G. M. Sheldrick, SHELX 97, University of Göttingen, 1997.
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