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DOI: 10.1039/A900761J (Paper) Reference Section for: J. Chem. Res. (S), 1999, 372-373

Studies on Pyrimidine-annulated Heterocycles: A New Short Synthesis of 7,9-Dialkylcyclohepta[b]pyrimido-[5,4-d]pyrrole-8(7H),10(9H)-dione Derivatives

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Makoto Nitta and Yohei Tajima

Abstract

A new short synthesis of 7,9-dialkylcyclohepta[b]pyrimido[5,4-d]pyrrole-8(7H),10(9H)-dione derivatives consists of the reaction of 6-amino-1,3-dialkyluracils with tropone, 2-halotropones and 2,6-dibromotropone in an enamine-alkylation process, subsequent condensation of the amino group with carbonyl function, and aromatization under the reaction conditions.

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