Total Partial Synthesis of (3S, 6S)-(+)-3,7-Dimethyl-6-hydroxy-3-acetoxyocta-1,7-diene and (3S, 6S)-(–)-3,7-Dimethylocta-1,7-diene-3,6-diol from Geraniol

Abstract

The synthesis of (3S, 6S)-(+)-3,7-dimethyl-6-hydroxy-3-acetoxyocta-1,7-diene and (3S, 6S)-(–)-3,7-dimethylocta-1,7-diene-3,6-diol via the rearrangement of the chiral 2,3-epoxy alcohol, with the system Ph₃P, pyridine, I₂ and H₂O, is described.

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