Chemoselective Hydrolysis of Esters by Fungal Lipase

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Abhijit Roy Chowdhury, Manish K. Tripathi, Umesh K. Jinwal, Uma Roy, Versha V. Kumar, A. P. Bhaduri and P. K. Roy


Abstract

Lipase, isolated from Aspergillus niger, exhibits chemoselectivity towards hydrolysis of fatty acid esters and does not hydrolyse carbamates; this has been demonstrated with substrates such as 5 (N-methoxycarbonyl-N-ethoxycarbonylmethylamino)-2-aryl-2,4-dihydro-3H-1,2,4-triazol-3-ones.


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