DOI: 10.1039/A802611D
(Paper)
Reference Section for: J. Chem. Res. (S), 1999, 10-11
Reaction of Carbon Disulfide with Cyanoacetic Acid Hydrazide: Novel Synthesis of Thiazole and Thiazolo[4,5-c]pyrazole
(Note: The full text of this document is currently only available in the PDF Version )
Rafat M. Mohareb, Suzan I. Aziz, Nadia I. Abdel-Sayed and Ahmed H. El-Banna
Abstract
The reaction of cyanoacetic acid hydrazide with carbon disulfide in basic dimethylformamide afforded the potassium thiocarbamate 2 which underwent ready heterocyclization upon its reaction with α-haloketones to give the thiazole derivatives 4 and 23.
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