Abu Zeid Abd El-Baset Hassanien, Ibrahim Saad Abdel Hafiz and Mohamed Hilmy Elnagdi
[(p-Sulfonamidophenyl)azo]malononitrile and/or [(p-sulfonamidophenyl)azo]acrylonitrile derivatives react with various reagents to afford pyrimidine, pyrazole, isooxazole and pyridazine derivatives with interesting biological activities via initial addition to either the cyano or amino group followed by cyclization.