Elemental analysis with quadrupole mass filters operated in higher stability regions

Abstract

Operation of quadrupole mass filters in higher zones of stability is described with an emphasis on the potential for elemental mass spectrometry. The higher zones allow a resolution at half height of up to 9000 on atomic ions and make possible unit resolution on ions with kinetic energies up to several thousand electron volts. The theory of quadrupole operation is briefly reviewed. Operation of quadrupoles in the third stability region with Mathieu parameters (a,q)≈(3,3) and the second stability region with (a,q)≈(0.02, 7.55) is described in detail. Previously unpublished data showing the variation of resolution with ion energy are presented. The variation of transmission with resolution is compared with previous calculations and with new calculations presented here.

References

1. Quadrupole Mass Spectrometry and Its Applications, ed. P. H. Dawson, Elsevier, Amsterdam, 1976, reprinted by A.I.P. Press, Woodbury, New York, 1995.
2. R. E. March and R. J. Hughes, Quadrupole Storage Mass Spectrometry, John Wiley and Sons, New York, 1989.
3. W. Paul, in Les Prix Nobels, Almqvist and Wiskell International, Stockholm, 1989.
4. N. V. Konenkov and V. I. Kratenko, Int. J. Mass Spectrom. Ion. Processes, 1991, 108, 115.
5. W. E. Austin, A. E. Holme and J. H. Leck, in Quadrupole Mass Spectrometry and Its Applications, ed. P. H. Dawson, Elsevier, Amsterdam, 1976, ch. 6, reprinted by A.I.P. Press, Woodbury, New York, 1995.
6. (a) V. V. Titov, J. Am. Soc. Mass Spectrom., 1998, 9, 50; (b) 1998, 9, 70.
7. D. J. Douglas and J. B. French, Spectrochim. Acta, Part B, 1986, 41, 197.
8. H. Niu and R. S. Houk, Spectrochim. Acta, Part B, 1996, 51, 779.
9. U. Von Zhan, Z. Physik., 1962, 168, 129.
10. (a) P. H. Dawson and N. R. Whetton, Int. J. Mass Spectrom. Ion Phys., 1969, 2, 45; (b) ibid. 1969, 3, 1.
11. (a) B. J. McIntosh and K. L. Hunter, Int. J. Mass Spectrom. Ion Processes, 1989, 87, 157; (b) J. F. Hennequin and R. L. Ingelbert, Int. J. Mass Spectrom. Ion Phys., 1978, 26, 131.
12. W. M. Brubaker, Adv. Mass Spectrom., 1968, 4, 293.
13. P. H. Dawson, Adv. Electronics Electron Phys., 1980, 53, 153.
14. N. V. Konenkov, V. I. Kratenko, G. A. Mogilchenko and S. S. Silakov, J. Tech. Phys. (Leningrad), 1989, 15, 23.
15. N. V. Konenkov, G. A. Mogilchenko, S. S. Silakov and G. I. Shagimuratov, Prib. Tekh. Eksp., 1990, No. 2, 179.
16. N. V. Konenkov, S. S. Silakov and G. A. Mogilchenko, J. Tech. Phys. (Leningrad), 1991, 17, 21.
17. (a) S. Hiroki, T. Abe and Y. Murakami, Rev. Sci. Instrum., 1991, 62, 2121; (b) S. Hiroki, T. Abe and Y. Murakami, 1992, 63, 3874; (c) S. Hiroki, T. Abe, Y. Murakami, K. Yanagashita and S. Nakamura, J. Vac. Sci. Tech., 1994, 12, 2711; (d) S. Hiroki, T. Abe and Y. Murakami, Rev. Sci. Instrum., 1994, 65, 1912; (e) S. Hiroki, T. Abe and Y. Murakami, Vacuum, 1996, 47, 767; (f) S. Hiroki, T. Abe and Y. Murakami, Int. J. Mass Spectrom. Ion Processes, 1994, 136, 85; (g) S. Hiroki, K. Sakata, N. Sugiyama, S. Muramoto, T. Abe and Y. Murakami, Vacuum, 1995, 46, 681.
18. R. E. Pedder and R. A. Schaeffer, Presented at the 43rd ASMS Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, May 21–26, 1995.
19. R. E. Pedder and R. A. Schaeffer, presented at the 44th ASMS Conference on Mass Spectrometry and Allied Topics, Portland, OR, USA, May 12–16, 1996.
20. Z. Du, T. N. Olney and D. J. Douglas, J. Am. Soc. Mass Spectrom., 1997, 8, 1230.
21. N. Konenkov, T. Kitaeva and P. Nikolski, Radiotekh. Electron. (Moscow), 1992, 37, 1528.
22. N. V. Konenkov, G. A. Mogilchenko, S. S. Silakov and G. H. Shagimuratov, J. Tech. Phys. (Leningrad), 1990, 60, 148.
23. D. J. Douglas, Z. Du and N. V. Konenkov, in preparation.
24. P. H. Dawson, J. Vac. Sci. Technol., 1974, 11, 1151.
25. (a) N. V. Konenkov, G. A. Mogilchenko and S. S. Silakov, J. Tech. Phys. (Leningrad), 1992, 62, 165; (b) N. V. Konenkov and J. T. Dowell, Int. J. Mass Spectrom. Ion Processes, 1997, 164, 201.
26. P. H. Dawson, Int. J. Mass Spectrom. Ion Processes, 1990, 100, 41.
27. N. V. Konenkov, Int. J. Mass Spectrom. Ion Processes, 1993, 123, 101.
28. V. V. Titov, presented at the 1998 Winter Conference on Plasma Spectrochemistry, Scottsdale, AZ, January 5–10, 1998.
29. (a) P. H. Dawson and Y. Binqi, Int. J. Mass Spectrom. Ion. Processes, 1984, 56, 25; (b) ibid., 1984, 56, 41.
30. G. I. Shagimuratov, N. V. Konenkov, G. A. Mogilchenko and S. S. Silakov, J. Tech. Phys. (Leningrad), 1990, 60, 112.
31. S. Hiroki, K. Kanenko and Y. Murakami, Vacuum, 1995, 46, 1445.
32. (a) G. R. Gillson, D. J. Douglas, J. E. Fulford, K. W. Halligan and S. D. Tanner, Anal. Chem., 1988, 60, 1472; (b) S. D. Tanner, Spectrochim. Acta, Part B, 1992, 47, 809.
33. (a) S. D. Tanner, L. M. Cousins and D. J. Douglas, Appl. Spectrosc., 1994, 48, 1367; (b) S. D. Tanner, D. J. Douglas and J. B. French, ibid., 1994, 48, 1373.
34. C. G. Grimm, R. Clawson and R. Short, J. Am. Soc. Mass Spectrom., 1997, 8, 539.
35. D. J. Douglas and N. V. Konenkov, J. Am. Soc. Mass Spectrom., 1998, in the press.
36. J.-F. Ying and D. J. Douglas, Rapid Commun. Mass Spectrom., 1996, 10, 649.
37. N. V. Nonenkov, Elektronic Tekh.: Ser: Electrovakh. Gasocydel. Apparat., 1991, 3, 14.
38. V. V. Titov, Int. J. Mass Spectrom. Ion Processes, 1995, 141, 57 see also the immediately preceding four papers by the same author in the same issue.