Metallobiosites and their synthetic analogues—a belief in synergism1997–1998 Tilden Lecture

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David E. Fenton


Abstract

Just as it is possible to use coordination compounds to try and gain insight into the nature of metallobiosites so it is also possible to use the knowledge acquired through crystallography concerning the structure of a metallobiosite to try to develop new chemistry. The aim of this lecture was to illustrate this philosophy by referring to the interplay that led to the confirmation of the dicopper site in haemocyanin and by speculating on the use of knowledge acquired concerning the dinuclear site in urease to facilitate simulation of the functioning of the site.


References

  1. J. B. Sumner, J. Biol. Chem., 1926, 69, 435 (J. Biol. Chem., 1926, 70, 97) CAS.
  2. R. J. P. Williams, Nature, 1974, 248, 302.
  3. N. E. Dixon, C. Gazzola, R. L. Blakeley and B. Zerner, J. Am. Chem. Soc., 1975, 97, 4130 CrossRef CAS; N. E. Dixon, P. W. Riddles, C. Gazola, R. L. Blakeley and B. Zerner, Can. J. Biochem., 1980, 58, 1335 CAS.
  4. E. Jabri, M. B. Carr, R. P. Hausinger and P. A. Karplus, Science, 1995, 268, 998 CrossRef CAS.
  5. H. A. O. Hill, Chem. Br., 1976, 12, 119 Search PubMed.
  6. K. D. Karlin, Science, 1993, 262, 1499.
  7. D. E. Fenton, M. Mercer, N. S. Poonia and M. R. Truter, J. Chem. Soc., Chem. Commun., 1972, 66 RSC.
  8. M. A. Bush and M. R. Truter, J. Chem. Soc., Perkin Trans. 2, 1972, 345 RSC.
  9. D. E. Fenton, Adv. Inorg. Bioinorg. Mech., 1983, 2, 187 Search PubMed and references therein.
  10. N. F. Curtis and D. A. House, Chem. Ind., 1961, 42, 1708 Search PubMed.
  11. J. D. Curry and D. H. Busch, J. Am. Chem. Soc., 1964, 86, 592 CrossRef CAS.
  12. E.-G. Jäger, Z. Chem., 1964, 4, 437.
  13. C. J. Pedersen, J. Am. Chem. Soc., 1967, 89, 7017 CrossRef CAS.
  14. D. E. Fenton, in Transition Metals in Supramolecular Chemistry, L. Fabbrizzi and A. Poggi(eds.), NATO ASI Series, Kluwer Academic Publishers, Dordrecht, 1994, C448, 153 and references therein Search PubMed.
  15. A. L. Vance, N. W. Alcock, D. H. Busch and J. A. Heppert, Inorg. Chem., 1997, 36, 5132 CrossRef CAS.
  16. E. I. Solomon, in Copper Coordination Chemistry: Biochemical and Inorganic Perspectives, K. D. Karlin and J. A. Zubieta(eds.), Academic Press, New York, 1983, p. 1 Search PubMed.
  17. N. A. Bailey, D. E. Fenton, R. Moody, C. O. Rodriguez de Barbarin, I. N. Sciambarella, J. M. Latour, D. Limosin and V. McKee, J. Chem. Soc., Dalton Trans., 1987, 2519 RSC.
  18. W. J. P. Gaykema, A. Volbeda and W. G. J. Hol, J. Mol. Biol., 1985, 187, 255; A. Volbeda and W. G. J. Hol, J. Mol. Biol., 1989, 209, 249 CAS.
  19. N. Kitajima, Adv. Inorg. Chem., 1992, 39, 1 CAS; N. Kitajima and W. B. Tolman, Progr. Inorg. Chem., 1995, 43, 533 Search PubMed and references therein.
  20. K. A. Magnus, H. Tonthat and J. E. Carpenter, Chem. Rev., 1994, 94, 727 CrossRef CAS and references therein.
  21. S. R. Collinson and D. E. Fenton, Coord. Chem. Rev., 1996, 48, 19 CrossRef and references therein.
  22. D. E. Fenton and G. Rossi, Inorg. Chim. Acta, 1985, 98, L29 CrossRef CAS; H. Adams, N. A. Bailey, W. D. Carlisle, D. E. Fenton and G. Rossi, J. Chem. Soc., Dalton Trans., 1990, 1271 RSC.
  23. N. A. Bailey, D. E. Fenton, P. C. Hellier, P. D. Hempstead, U. Casellato and P. A. Vigato, J. Chem. Soc., Dalton Trans., 1992, 2809 RSC.
  24. V. V. Barynin, A. A. Vagin, V. R. Melik-Adamyan, A. I. Grebenko, S. V. Khangulov, A. N. Popov, M. E. Andrionova and B. K. Vainshtein, Dokl. Akad. Nauk. SSSR, 1986, 288, 877 Search PubMed.
  25. E. E. Kim and H. W. Wyckoff, J.Mol. Biol., 1991, 218, 449 CrossRef CAS.
  26. E. Hough, L. K. Hansen, R. Birknes, K. Jynge, S. Hansen, A. Hordvik, C. Little, E. J. Dodson and Z. Derewanda, Nature (London), 1989, 338, 357 CrossRef CAS.
  27. N. Sträter, T. Klabunde, P. Tucker, H. Witzel and B. Krebs, Science, 268 1995, 1489 Search PubMed.
  28. M.-P. Egloff, P. T. W. Cohen, P. Reinemer and D. Barford, J. Mol. Biol., 1995, 254, 942 CrossRef CAS.
  29. B. L. Vallee and D. S. Auld, Biochemistry, 1993, 32, 6493 CrossRef CAS.
  30. J. H. Satcher, Jr., M. W. Droege, T. J. R. Weakley and R. T. Taylor, Inorg. Chem., 1995, 34, 3317 CrossRef.
  31. T. N. Sorrell, Tetrahedron, 1989, 45, 3 CrossRef.
  32. D. E. Fenton, Adv. Inorg. Bioinorg. Mech., 1983, 2, 187 Search PubMed and references therein.
  33. D. E. Fenton and H. Okawa, Chem. Ber/Recl., 1997, 130, 433 CrossRef CAS and references therein.
  34. A. W. Addison, T. N. Rao, J. Reedijk, J. van Rijn and G. C. Verschoor, J. Chem. Soc., Dalton Trans., 1984, 1349 RSC.
  35. M. Lubben and B. L. Feringa, J. Org. Chem., 1994, 59, 2227 CrossRef CAS; M. Lubben, R. Hage, A. Meetsma, K. Byma and B. L. Feringa, Inorg. Chem., 1995, 34, 2217 CrossRef CAS.
  36. J. Reim and B. Krebs, J. Chem. Soc., Dalton Trans., 1997, 3793 RSC.
  37. H. Wada, K. Motoda, M. Ohba, H. Sakiyama, N. Matsumoto and H. Okawa, Bull. Chem. Soc. Jpn., 1995, 68, 1105 CAS and references therein..
  38. E. Lambert, B. Chabut, S. Chardon-Noblat, A. Deronzier, G. Chottard, A. Bousseksou, J.-P. Tuchagues, J. Laugier, M. Dardet and J.-M. Latour, J. Am. Chem. Soc., 1997, 119, 9424 CrossRef CAS.
  39. D. E. Fenton, S. R. Haque, D. Dye, H. Adams, S. L. Heath, N. Fukita, M. Ohba and H. Okawa, unpublished results.
  40. T. Koga, H. Furutachi, T. Nakamura, N. Fukita, M. Ohba, K. Takahashi and H. Okawa, Inorg. Chem., 1998, 37, 989 CrossRef CAS.
  41. S. Uozumi, H. Furutachi, M. Ohba, H. Okawa, D. E. Fenton, K. Shindo, M. Murata and D. J. Kitko, Inorg. Chem., 1998, 37, 6281 CrossRef CAS.
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