Design, synthesis and self-association behavior of water soluble self complementary facial amphiphiles

Abstract

Self-complementary facially amphiphilic derivatives of glycoluril are useful building blocks for hydrophobic self-assembly in water; we describe the design, synthesis and characterization of six dimeric self-assembled structures with values of K_S up to 1840 M^–1 in pD 7.4 buffered D₂O.

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