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DOI: 10.1039/A906579B (Paper) Reference Section for: Chem. Commun., 1999, 2251-2252

Synthesis of racemic brevioxime

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Derrick L. J. Clive and Soleiman Hisaindee

Abstract

Amine hydrochloride 12 and β-keto thioester 16 were coupled and treated with TFA; the resulting alcohols 18 were oxidized and converted into a mixture of oximes 20, from which the major product, racemic brevioxime 1, was isolated.

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