Copper(II), in the parts per million range, modulates photochemical and photosensitizing properties of tolmetin via electron transfer with a triplet carbanion

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S. Sortino, G. De Guidi, L. L. Costanzo, S. Sortino and J. C. Scaiano


Abstract

Copper(II), at very low levels of concentration, modulates the distribution of tolmetin stable photoproducts as well as inhibits the DNA cleavage photoinduced by the drug, via a highly efficient electron transfer process with the main transient species generated in the tolmetin photolysis.


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