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DOI: 10.1039/A905678E (Paper) Reference Section for: Chem. Commun., 1999, 1809-1810

Extremely selective Mg(ClO4)2 mediated removal of Bpoc/Ddz moieties suitable for the solid phase peptide synthesis of thioxo peptides

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Dirk Wildemann, Mario Drewello, Gunter Fischer and Mike Schutkowski

Abstract

Mg(ClO4)2 in organic solvents acts as an extremely mild reagent for repetitive Bpoc/Ddz deprotection during solid phase peptide synthesis even in the presence of the acid labile thioxo amide moiety with excellent yields.

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