Regio- and enantio-selective Heck reactions of aryl and alkenyl triflates with the new chiral ligand (R)-BITIANP

Abstract

The Heck reaction of dihydrofuran 3 with aryl triflates 4 and 6a–d and alkenyl triflate 8 in the presence of the chiral ligand (R)-BITIANP 1 provides the 2-substituted 2,3-dihydrofurans 5a, 7a–d and 9, respectively, with complete regioselectivity, high enantioselectivity (86–96% ee) and good yields (76–93%).

References

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