PtII coordination to guanine-N7: enhancement of the stability of the Watson–Crick base pair with cytosine
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Roland K. O. Sigel and Bernhard Lippert
Abstract
Concentration-dependent 1H NMR shift experiments in (CD3)2SO reveal that PtII-coordination to N7 of guanine enhances the stability of the Watson–Crick pair with cytosine.
References
W. Saenger,
Principles of Nucleic Acid Structure,
Springer,
New York,
1984 Search PubMed.
G. L. Eichhorn and Y. A. Shin, J. Am. Chem. Soc., 1968, 90, 7323 CrossRefCAS.
J. Sponer, M. Sabat, J. V. Burda, A. M. Doody, J. Leszczynski and P. Hobza, J. Biomol. Struct. Dyn., 1998, 16, 139 Search PubMed; J. Sponer, J. V. Burda, M. Sabat, J. Leszczynski and P. Hobza, J. Phys. Chem. A, 1998, 102, 5951 CrossRefCAS; J. V. Burda, J. Sponer, J. Leszczynski and P. Hobza, J. Phys. Chem. B, 1997, 101, 9670 CrossRefCAS; J. Sponer, J. V. Burda, P. Mejzlik, J. Leszczynski and P. Hobza, J. Biomol. Struct. Dyn., 1997, 14, 613 Search PubMed.
E. H. S. Anwander, M. M. Probst and B. M. Rode, Biopolymers, 1990, 29, 757 CrossRefCAS.
S. R. Gadre, S. S. Pundlik, A. C. Limaye and A. P. Rendell, Chem. Commun., 1998, 573 RSC.
V. N. Potaman and V. N. Soyfer, J. Biomol. Struct. Dyn., 1998, 16, 145 Search PubMed; V. N. Potaman and V. N. Soyfer, J. Biomol. Struct. Dyn., 1994, 11, 1035 Search PubMed.
G. Schröder, B. Lippert, M. Sabat, C. J. L. Lock, R. Faggiani, B. Song and H. Sigel, J. Chem. Soc., Dalton Trans., 1995, 3767 RSC.
H.-K. Choi, S. K.-S. Huang and R. Bau, Biochem. Biophys. Res. Commun., 1988, 156, 1125 CAS; I. Dieter-Wurm, M. Sabat and B. Lippert, J. Am. Chem. Soc., 1992, 114, 357 CrossRefCAS.
P. M. Takahara, C. A. Frederick and S. J. Lippard, J. Am. Chem. Soc., 1996, 118, 12309 CrossRefCAS.
D. Yang, S. S. G. E. van Boom, J. Reedijk, J. H. van Boom and A. H.-J. Wang, Biochemistry, 1995, 34, 12912 CrossRefCAS and references therein.
F. Herman, J. Kozelka, V. Stoven, E. Guittet, J.-P. Girault, T. Huynh-Dinh, J. Igolen, J.-Y. Lallemand and J.-C. Chottard, Eur. J. Biochem., 1990, 194, 119 CAS.
G. Frommer, H. Schöllhorn, U. Thewalt and B. Lippert, Inorg. Chem., 1990, 29, 1417 CrossRefCAS.
R. K. O. Sigel, M. Sabat, E. Freisinger, A. Mower and B. Lippert, Inorg. Chem., 1999, 38, 1481 CrossRefCAS.
Synthesis of the 1-methylthymine containing complex 3 (ClO4– salt) is
in analogy to the corresponding 1-methyluracil compound: R. K. O. Sigel, S. M. Thompson, E. Freisinger and B. Lippert, Chem. Commun., 1999, 19 Search PubMed.
R. Newmark and C. R. Cantor, J. Am. Chem. Soc., 1968, 90, 5010 CrossRefCAS.
R. Zaludova, V. Kleinwächter and V. Brabec, Biophys. Chem., 1996, 60, 135 CrossRefCAS; V. Brabec, J. Reedijk and M. Leng, Biochemistry, 1992, 31, 12397 CrossRefCAS.
J. P. Macquet,
J. L. Butour and
N. P. Johnson, in
Platinum, Gold, and Other Metal Chemotherapeutic Agents,
ed. S. J. Lippard,
American Chemical Society,
Washington, DC,
1983,
p. 75 Search PubMed.
H. Sigel, K. H. Scheller, V. M. Rheinberger and B. E. Fischer, J. Chem. Soc., Dalton Trans., 1980, 1022 RSC.
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