Non-peptidic liposome-fusion compounds at acidic pH

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Yoshikatsu Ogawa, Takenori Tomohiro, Masato Kodaka, Hiroaki Okuno and Yoshimitsu Yamazaki


Abstract

Liposomes including aspartic acid-derived artificial lipids (ADL) with various carboxy alkyl chains as head groups (ADLn; n indicates the number of the methylene groups, n = 2,4,6,8,10,12) are prepared, in which ADL6 and ADL8 liposomes induce remarkably high lipid-mixing in the acidic region.


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